p. 221 - 233 QUELQUES PROPRIETES CHIMIQUES ET PHARMACOLOGIQUES DE L'INHIBITEUR NATUREL DE PEPSINE EXTRAIT ET PURIFIE DU GASTROPODE MARIN Rapana Thomasiana GROSSE Natalia Rosoiu 1), A. Cristea 2), M. Zodianu 2), Maria Panait 1) 1) Institut Roumain de Recherches Marines Constanta 2) Institut de Recherches Chimico-Pharmaceutiques Bucharest Abstract The paper presents data on biological compound and some pharmacological properties of the natural inhibitor of pepsin that was separated and purified from the marine gastropode Rapana thomasiana GROSSE. The natural inhibitor of pepsin develops an intensive activity of pepsin inhibition and displayng very important pharmaco- logical properties.