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STATISTICAL METHOD OF ASSIGNING FIDUCIDAL LIMITS TO A
PROTECTIVE EFFECT ESTIMATED FROM BIOLOGICAL ASSAYS WHICH
COMPARE THREE GROUPS OF RESULTS

M. Siminovici, A.I. Molnar, N. Bonciocat 
Chemical-Pharmaceutical Research Institute
Bucuresti, 4, Vitan 112

Abstract
A statistical method of assigning fiducidal limits to a protective
effect is proposed. The method is based on a theorem of mathemartical
statistics given by Fieller, and may be applied to all experimental
procedures which measure an adequate quantitative response in three
groups of animals: intoxicated animals, intoxicated and treated
animals, and control animals.
A numerical example of assigning fiducidal limits to the antilipical
effect of the mucopolysaccharide extracted from Mytilus
galloprovincialis in the intoxication with Triton, is also given.